MTHFR gene variant blood test at St Helena Hospital

Hospitals report these codes with terse, inconsistent chargemaster text. This plain-English title was written by an AI model from that text and has not been reviewed by a person, so it can be wrong. The prices on this page come straight from hospital filings and do not depend on it.

Model: claude-haiku-5-5
Provider: anthropic
API: message_batches
Reasoning effort: low
Max output tokens: 4096
Prompt version (hash): 444523875572
Generated: October 20, 2026

Original text from hospital filings

Gene analysis (5, 10-methylenetetrahydrofolate reductase) common variants

Helena, CA

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Pricing by billing methodology

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How this price compares nationally

St Helena Hospital’s median price of $54 is 38% below the median hospital's median price ($87), higher than 6% of the 2,400 hospitals reporting CPT 81291. The highlighted bar is where this hospital falls; shaded is the middle 50% of hospitals.

Payers reporting CPT 81291 at St Helena Hospital

Negotiated rates from the hospital’s own file: 6 payers, 20 plan rates. A facility fee, a professional fee, a per diem and a case rate are different bills, so each is listed on its own. Open a payer to see it across hospitals.

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1	UnitedHealthcare uhc select/select plus percent of total billed charges · outpatientfrom % of charges	$29	$29	—	—	—	$29 – $29
2	Blue Cross Blue Shield blue shield behav hlth percent of total billed charges · outpatientfrom % of charges	$29	$29	—	—	—	$29 – $29
3	Blue Cross Blue Shield blue shield non-epn percent of total billed charges · outpatientfrom % of charges	$30	$30	—	—	—	$30 – $30
4	Blue Cross Blue Shield blue shield epn-all other plans percent of total billed charges · outpatientfrom % of charges	$31	$31	—	—	—	$31 – $31
5	UnitedHealthcare uhc jll percent of total billed charges · outpatientfrom % of charges	$31	$31	—	—	—	$31 – $31
6	UnitedHealthcare uhc all payer - all other plans percent of total billed charges · outpatientfrom % of charges	$33	$33	—	—	—	$33 – $33
7	Phcs phcs-all plans percent of total billed charges · outpatientfrom % of charges	$36	$36	—	—	—	$36 – $36
8	UnitedHealthcare umr uhc ppo percent of total billed charges · outpatientfrom % of charges	$42	$42	—	—	—	$42 – $42
9	UnitedHealthcare uhc options ppo percent of total billed charges · outpatientfrom % of charges	$42	$42	—	—	—	$42 – $42
10	Cigna cigna-all other plans percent of total billed charges · outpatientfrom % of charges	$52	$52	—	—	—	$52 – $52
11	Kaiser kaiser-all other plans percent of total billed charges · outpatientfrom % of charges	$54	$54	—	—	—	$54 – $54
12	Blue Cross Blue Shield blue shield bh mcr adv other · outpatient	$65	$65	—	—	—	$65 – $65
13	Blue Cross Blue Shield blue shield mcr adv other · outpatient	$65	$65	—	—	—	$65 – $65
14	Blue Cross Blue Shield tricare blue shield other · outpatient	$65	$65	—	—	—	$65 – $65
15	Kaiser kaiser mcr adv other · outpatient	$65	$65	—	—	—	$65 – $65
16	UnitedHealthcare uhc mcr adv other · outpatient	$65	$65	—	—	—	$65 – $65
17	Aetna aetna-all plans fee schedule · outpatient	$245	$245	—	—	—	$245 – $245
18	Blue Cross Blue Shield blue cross exchange fee schedule · outpatient	$379	$379	—	—	—	$379 – $379
19	Blue Cross Blue Shield blue cross non mcs fee schedule · outpatient	$421	$421	—	—	—	$421 – $421
20	Blue Cross Blue Shield blue cross mcs - all other plans fee schedule · outpatient	$506	$506	—	—	—	$506 – $506

Last updated: Jul 15, 2026

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See MTHFR gene variant blood test pricing across every hospital in the network reporting it, or ask Claude or any MCP client directly — see how to connect.