Hospitals report these codes with terse, inconsistent chargemaster text. This plain-English title was written by an AI model from that text and has not been reviewed by a person, so it can be wrong. The prices on this page come straight from hospital filings and do not depend on it.
Original text from hospital filings
Methylation analysis (small nuclear ribonucleoprotein polypeptide N and ubiquitin protein ligase E3A)
Spearfish, SD
See all hospitals reporting CPT 81331 →Price type
Monument Health Network Inc’s median price of $550 is 757% above the median hospital's median price ($64), higher than 96% of the 1,852 hospitals reporting CPT 81331. The highlighted bar is where this hospital falls; shaded is the middle 50% of hospitals.
Negotiated rates from the hospital’s own file: 4 payers, 8 plan rates. A facility fee, a professional fee, a per diem and a case rate are different bills, so each is listed on its own. Open a payer to see it across hospitals.
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| # | |||||||
|---|---|---|---|---|---|---|---|
| 1 | UnitedHealthcare uhc mcr adv other · outpatient | $51 | $51 | — | — | — | $51 – $51 |
| 2 | UnitedHealthcare uhc - all other plans fee schedule · outpatient | $61 | $61 | — | — | — | $61 – $61 |
| 3 | Wellmark bcbs wellmark - all other plans fee schedule · outpatient | $133 | $133 | — | — | — | $133 – $133 |
| 4 | Medica medica mcaid percent of total billed charges · outpatientfrom % of charges | $202 | $202 | — | — | — | $202 – $202 |
| 5 | Medica medica mcr adv percent of total billed charges · outpatientfrom % of charges | $254 | $254 | — | — | — | $254 – $254 |
| 6 | Medica medica commercial - all other plans percent of total billed charges · outpatientfrom % of charges | $566 | $566 | — | — | — | $566 – $566 |
| 7 | MultiPlan multiplan/phcs - all plans percent of total billed charges · outpatientfrom % of charges | $654 | $654 | — | — | — | $654 – $654 |
| 8 | Wellmark bcbs wellmark mcr adv other · outpatient | $705 | $705 | — | — | — | $705 – $705 |
Last updated: Sep 1, 2026
See Methylation test for Prader-Willi or Angelman syndrome pricing across every hospital in the network reporting it, or ask Claude or any MCP client directly — see how to connect.