MTHFR gene variant blood test at Medical City Plano

Hospitals report these codes with terse, inconsistent chargemaster text. This plain-English title was written by an AI model from that text and has not been reviewed by a person, so it can be wrong. The prices on this page come straight from hospital filings and do not depend on it.

Model: claude-haiku-5-5
Provider: anthropic
API: message_batches
Reasoning effort: low
Max output tokens: 4096
Prompt version (hash): 444523875572
Generated: October 20, 2026

Original text from hospital filings

MTHFR (5,10-methylenetetrahydrofolate reductase) (eg, hereditary hypercoagulability) gene analysis, common variants (eg, 677T, 1298C)

Plano, TX

See all hospitals reporting CPT 81291 →

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Pricing by billing methodology

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How this price compares nationally

Medical City Plano’s median price of $98 is 13% above the median hospital's median price ($87), higher than 56% of the 2,400 hospitals reporting CPT 81291. The highlighted bar is where this hospital falls; shaded is the middle 50% of hospitals.

Payers reporting CPT 81291 at Medical City Plano

Negotiated rates from the hospital’s own file: 14 payers, 75 plan rates. A facility fee, a professional fee, a per diem and a case rate are different bills, so each is listed on its own. Open a payer to see it across hospitals.

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1	UnitedHealthcare chip fee schedule · outpatient	$55	$55	—	—	—	$55 – $55
2	UnitedHealthcare star fee schedule · outpatient	$55	$55	—	—	—	$55 – $55
3	UnitedHealthcare starkids fee schedule · outpatient	$55	$55	—	—	—	$55 – $55
4	UnitedHealthcare starperinate fee schedule · outpatient	$55	$55	—	—	—	$55 – $55
5	UnitedHealthcare starplus fee schedule · outpatient	$55	$55	—	—	—	$55 – $55
6	Cigna Healthspring mgmcd fee schedule · outpatient	$58	$58	—	—	—	$58 – $58
7	Aetna Better Health chip fee schedule · outpatient	$59	$59	—	—	—	$59 – $59
8	Aetna Better Health mcd fee schedule · outpatient	$59	$59	—	—	—	$59 – $59
9	Molina chip fee schedule · outpatient	$61	$61	$1	1%	—	$60 – $61
10	Molina mcdstar fee schedule · outpatient	$61	$61	$1	1%	—	$60 – $61
11	Molina star+plus fee schedule · outpatient	$61	$61	$1	1%	—	$60 – $61
12	Molina starkids fee schedule · outpatient	$61	$61	$1	1%	—	$60 – $61
13	Blue Cross Blue Shield mcrppo fee schedule · outpatient	$65	$65	—	—	—	$65 – $65
14	Blue Cross Blue Shield mgmcrhmo fee schedule · outpatient	$65	$65	—	—	—	$65 – $65
15	Devoted hmo fee schedule · outpatient	$65	$65	—	—	—	$65 – $65
16	Devoted mcr fee schedule · outpatient	$65	$65	—	—	—	$65 – $65
17	Devoted mme fee schedule · outpatient	$65	$65	—	—	—	$65 – $65
18	Devoted pos fee schedule · outpatient	$65	$65	—	—	—	$65 – $65
19	Devoted ppo fee schedule · outpatient	$65	$65	—	—	—	$65 – $65
20	Devoted snp fee schedule · outpatient	$65	$65	—	—	—	$65 – $65
21	Humana mgmcr fee schedule · outpatient	$65	$65	—	—	—	$65 – $65
22	UnitedHealthcare allpayerappendix fee schedule · outpatient	$65	$65	—	—	—	$65 – $65
23	UnitedHealthcare narrownetworkindivexchange fee schedule · outpatient	$65	$65	—	—	—	$65 – $65
24	UnitedHealthcare smallgroup fee schedule · outpatient	$65	$65	—	—	—	$65 – $65
25	UnitedHealthcare mgmcr fee schedule · outpatient	$66	$66	—	—	—	$66 – $66

Page 1 of 3 · 75 rates

Last updated: Mar 1, 2026

Compare to other hospitals

See MTHFR gene variant blood test pricing across every hospital in the network reporting it, or ask Claude or any MCP client directly — see how to connect.