Hospitals report these codes with terse, inconsistent chargemaster text. This plain-English title was written by an AI model from that text and has not been reviewed by a person, so it can be wrong. The prices on this page come straight from hospital filings and do not depend on it.
Original text from hospital filings
HC PRADER WILLI/ANGELMANSYNDROME DNA METHYLAT
Lancaster, PA
See all hospitals reporting CPT 81331 →Price type
Lancaster General Health’s median price of $208 is 224% above the median hospital's median price ($64), higher than 84% of the 1,852 hospitals reporting CPT 81331. The highlighted bar is where this hospital falls; shaded is the middle 50% of hospitals.
Negotiated rates from the hospital’s own file: 12 payers, 33 plan rates. A facility fee, a professional fee, a per diem and a case rate are different bills, so each is listed on its own. Open a payer to see it across hospitals.
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| # | |||||||
|---|---|---|---|---|---|---|---|
| 1 | Highmark highmark medicare advantage facility · fee schedule · outpatient | $51 | $51 | — | — | — | $51 – $51 |
| 2 | Medicare medicare facility · fee schedule · outpatient | $51 | $51 | — | — | — | $51 – $51 |
| 3 | UnitedHealthcare united healthcare med adv facility · fee schedule · outpatient | $51 | $51 | — | — | — | $51 – $51 |
| 4 | Aetna aetna medicare advantage facility · other · outpatient | $52 | $52 | — | — | — | $52 – $52 |
| 5 | Blue Cross Blue Shield cbc medicare advantage facility · fee schedule · outpatient | $52 | $52 | — | — | — | $52 – $52 |
| 6 | Amerihealth Caritas amerihealth caritas med adv facility · fee schedule · outpatient | $52 | $52 | — | — | — | $52 – $52 |
| 7 | Blue Cross Blue Shield independence blue cross medicare advantage facility · other · outpatient | $52 | $52 | — | — | — | $52 – $52 |
| 8 | Cigna Healthspring cigna healthspring facility · fee schedule · outpatient | $53 | $53 | — | — | — | $53 – $53 |
| 9 | Devoted devoted health medicare advantage facility · other · outpatient | $54 | $54 | — | — | — | $54 – $54 |
| 10 | Amerihealth Caritas amerihealth caritas medicaid hmo facility · fee schedule · outpatient | $68 | $68 | — | — | — | $68 – $68 |
| 11 | Medicaid medicaid facility · fee schedule · outpatient | $68 | $68 | — | — | — | $68 – $68 |
| 12 | UnitedHealthcare united healthcare medicaid mco facility · case rate · outpatient | $75 | $75 | — | — | — | $75 – $75 |
| 13 | Blue Cross Blue Shield cbc commercial facility · fee schedule · outpatient | $95 | $95 | — | — | — | $95 – $95 |
| 14 | Oscar oscar health plan facility · other · outpatient | $100 | $100 | — | — | — | $100 – $100 |
| 15 | UnitedHealthcare united healthcare commercial facility · fee schedule · outpatient | $102 | $102 | — | — | — | $102 – $102 |
| 16 | Highmark highmark chip facility · other · outpatient | $162 | $162 | — | — | — | $162 – $162 |
| 17 | Highmark highmark aca facility · other · outpatient | $195 | $195 | — | — | — | $195 – $195 |
| 18 | Highmark highmark commercial preferred facility · other · outpatient | $224 | $224 | — | — | — | $224 – $224 |
| 19 | Blue Cross Blue Shield independence blue cross commercial facility · percent of total billed charges · outpatientfrom % of charges | $233 | $233 | — | — | — | $233 – $233 |
| 20 | Cigna cigna new business facility · fee schedule · outpatient | $255 | $255 | — | — | — | $255 – $255 |
| 21 | Highmark highmark commercial facility · other · outpatient | $279 | $279 | — | — | — | $279 – $279 |
| 22 | Highmark highmark commercial non-preferred facility · other · outpatient | $338 | $338 | — | — | — | $338 – $338 |
| 23 | Cigna cigna facility · percent of total billed charges · inpatientfrom % of charges | $537 | $537 | — | — | — | $537 – $537 |
| 24 | Cigna cigna facility · percent of total billed charges · outpatientfrom % of charges | $595 | $595 | — | — | — | $595 – $595 |
| 25 | Blue Cross Blue Shield independence blue cross commercial facility · percent of total billed charges · inpatientfrom % of charges | $604 | $604 | — | — | — | $604 – $604 |
Last updated: Mar 31, 2026
See Methylation test for Prader-Willi or Angelman syndrome pricing across every hospital in the network reporting it, or ask Claude or any MCP client directly — see how to connect.